TABLE 3.

Correct answer rates regarding clinical knowledge after the EGUIDE program with the CPG for major depressive disorder

Major depressive disorder	Items	2016 (%)	2017 (%)	P value
Diagnosis of major depressive disorder (DSM‐5)
Depressed mood and a loss of interest or pleasure most of the day, nearly every day should be present over the same two‐week period for the diagnosis [incorrect]	D‐A1	56.5	60.8	0.44
Treatment of major depressive disorder
The safety of antidepressants during pregnancy has not been not determined, so more attention to adverse effects should be paid when antidepressants are administered to young people than to the elderly [incorrect]	D‐B5	47.6	51.1	0.52
Management of mild depression
Antidepressants are not recommended when patients expect to receive psychotherapy [correct]	D‐C5	71.4	65.9	0.3
Antidepressant use should be avoided when patients have multiple depressive episodes [incorrect]	D‐C6	85.7	93.2	0.033
Recommended treatment for moderate/severe depression
Combination of antidepressants and benzodiazepines or atypical antipsychotics with adequate doses and duration [incorrect]	D‐D3	78.6	89.2	8.0 × 10‐3

The rates of correct answers after the EGUIDE program for each item were compared using Fisher's exact tests. The P‐values are boldfaced (P < 0.05) and underlined (P < 0.01). The statistical significance level was set at P < 0.01 for correction of multiple testing of five items.