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. 2021 Mar 6;41(2):230–236. doi: 10.1002/npr2.12167

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© 2021 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of Neuropsychopharmacology

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Changes in the mRNA levels of neuroinflammation‐associated genes in the hippocampus and cortex of Mg²⁺ deficiency (MgD) mice. (A) Changes in mRNA levels in the hippocampus of MgD mice. Angptl7, H2‐Q7, Timp1, Cxcl10, Ccl5, and Ccl7 (control [Ctrl], n = 8; MgD, n = 6) and Spp1 (Ctrl, n = 11; MgD, n = 9). (B) Increases in mRNA levels in the cortex of MgD mice (Ctrl, n = 8; MgD, n = 7). (C) No changes in the mRNA levels of M1 (Cd16, Cd32) and M2 (Cd206, Cd209a) microglia markers in the hippocampus of MgD mice (Ctrl, n = 11; MgD, n = 9). (D) Changes in the mRNA levels of microglia markers in the cortex of MgD mice (Ctrl, n = 8; MgD, n = 7). *P < 0.05. Error bars indicate standard error of the mean.