Table 4.
Re-analysis of Additional Male Female Difference In Lymphocyte mRNA in Earlier Published Sample (Auta et al, 2013)
| mRNA | Schizophrenics (CSZ) | Controls (NPC) | Test |
|---|---|---|---|
| DNMT1 | |||
| Total Sample | 65.80 ± 24.43 (n=27) | 49.65 ±16.88 (n=20) | TU=2.68, df=44.8, P=0.01 |
| Male | 71.93 ± 23.73 (n=21) | 54.60 ± 17.78 (n=10) | T=2.05 df=29, P=0.05 |
| Female | 44.33 ± 11.76 (n=6) | 44.70 ±15.20 (n=10) | T=.050, df=14, P=0.96 |
| TET1 | |||
| Total Sample | 2.73 ±1.09 (n=25) | 1.82± 0.79 (n=18) | T=3.00, df=41, P=0.005 |
| Male | 2.82 ±1.17 (n=20) | 1.76 ± 0.70 (n=7) | T=2.25, df=25, P=0.034 |
| Female | 2.35 ± 0.69 (n=5) | 1.86± 0.87 (n=11) | T=1.110, df=14, P=0.29 |
| BDNF | |||
| Total Sample | 0.26 ± 0.15 (n=18) | 0.38 ± 0.16 (n=11) | T=2.01, df=27, P=0.055 |
| Male | 0.22 ± 0.10 (n=11) | 0.44 ± 0.18 (n=5) | T=3.32, df=14, P=0.005 |
| Female | 0.34 ± 0.19 (n=7) | 0.33 ± 0.13 (n=6) | T=0.11, df=11, P=0.91 |
Each value represents Mean ± S.D. T= independent sample T-test. TU= independent sample T-test for unequal variances.