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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Biomark Neuropsychiatry. 2021 Jun 24;5:100038. doi: 10.1016/j.bionps.2021.100038

Table 6.

Correlations Between DNMT mRNAs and GABAergic, BDNF and Glucocorticoid mRNAs.

mRNA DNMT1(or) (L) DNMT1-cus DNMT3A
All Subjects CSZ NPC All Subjects CSZ NPC All Subjects CSZ NPC
GAD1(L) +0.043 −0.058 +0.097 +0.177 +0.117 −0.074 +0.023 −0.010 −0.268
GAD67(Ln) +0.282* +0.070 +0.492** +0.075 +0.052 +0.022 +0.201 +0.120 +0.079
BDNF (bc) (L) +0.053 +0.27O −0.210 +0.156 +0.089 +0.009 +0.514***B +0.600***B +0.344
BDNFIX (L) +0.352**B +0.373 +0.296 +0.266*B +0.256 +0.253 +0.544***B +0.589***B +0.502**B
NR3C1 (bc) (SR) +0.106 +0.319 +0.106 +0.537***B +.0.465**B +0.504**B +0.459***B +0.394*B +0.437*B
NR3C1-cus +0.359**B +0.451* +0.220 +0.560***B +0.543***B +0.561***B +0.541***B +0.518**B 0.490**B

Each number is Pearson (r) correlation between indicated mRNAs measured in lymphocytes. N’s All subjects 52–71, Schizophrenics 25–38, NPC controls 27–33. Transformations: (L)=log10, (Ln)= Log2, SR= square root. Significance:

*

P<.05,

**

P≤.01,

***

P≤.001.

B

= survived protected significance level with BH procedure (α=.05) using the 6 mRNA comparisons. Nonparametric correlations (rho) on non-transformed values were in the same range.