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. 2021 Jul 22;12:704074. doi: 10.3389/fphar.2021.704074

TABLE 4.

Effect of BSTN1 on FBG, PPBG, F-Ins and HOMA-IR in treated and untreated rats.

Parameters Normal control HFD control BSTN1-1.25 mg BSTN1-2.5 mg BSTN1-5 mg ORL-5 mg
FBG (mg/dl) 86.12 ± 4.6 159.6 ± 8.0# 133.0 ± 6.1* 115.1 ± 9.2** 91.2 ± 7.1*** 97.3 ± 6.9***
PPBG (mg/dl) 99.6 ± 5.0 211.1 ± 9.4# 174.6 ± 3.7* 141.5 ± 8.7** 100.3 ± 5.7*** 104.7 ± 3.9***
F-Ins (µIU/ml) 14.57 ± 1.8 18.07 ± 1.3# 15.33 ± 2.1* 15.09 ± 2.0** 14.72 ± 1.7*** 14.94 ± 1.1***
HOMA-IR 3.1 7.1# 5.0* 4.3** 3.3*** 3.6***

# p < 0.001 indicates significant difference between HFD control and normal control. *, ** and *** indicate significant difference between HFD control and treated groups at p < 0.05, p < 0.01, and p < 0.001, respectively. FBG, fasting blood glucose; PPBG, post-prandial blood glucose; F-Ins, fasting insulin; HOMA-IR, homeostasis model assessment index for insulin resistance.