Thermal denaturation studies (T_m values) of SUL-ODN duplexes and their half-life evaluations against EcoR1 and SVPDE (once the modified nucleoside was reached)³⁵⁴.

Hybridized duplexa	T m (°C)	t 1/2 b
		EcoR1 (min)	SVPDE + CIAP
5′-GAGCTCGAATTCACTGGCCG-3′	73	30	—
3′-CTCGAGCTTAAGTGACCGGC-5′
5′-GAGCTCGSULAATTCACTGGCCG-3′	70	>60	>60
3′-CTCGAGCTTAASULGTGACCGGC-5′

^aSUL refers to the sulfamate internucleoside linkage.

^bODN not tested.