. 2020 Dec 8;2(1):94–150. doi: 10.1039/d0cb00136h

Thermal denaturation studies (T_m values) of AM-ODN with complementary DNA or RNA and their half-life evaluations against FBS³⁹⁵.

ODN (5′ → 3′)^a	T _m with DNA (°C)	T _m with RNA (°C)	t _1/2 ^b (h)
d(TTTTTCCTGATAGTTTTT)	55.5	56.1	<1
d(T_AMT_AMT_AMT_AMTCCTGATAGT_AMT_AMT_AMT_AMT)	52.3	54.6	∼6
d(U̲U̲U̲U̲U̲CCTGATAGU̲U̲U̲U̲U̲)	47.8	58.6	<1

AM and U̲ refer to the amide internucleoside linkage and 2′-OMe-uridine respectively.

Approximate values based on raw data.

Thermal denaturation studies (Tm values) of AM-ODN with complementary DNA or RNA and their half-life evaluations against FBS395.