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. 2020 Dec 8;2(1):94–150. doi: 10.1039/d0cb00136h

Percentages of ORN degradation catalyzed by RNase-H86.

ORN component (ORN : ODN molar ratio)a Incubation temperature (°C) ODN componentb
All-PO Mix-PS All-Rp-PS All-Sp-PS
ORN-all-PO (1 : 1) 37 87 53 89 52
ORN-all-PO (1 : 3) 37 96 83 96 75
ORN-all-PO (1 : 3) 28 80 65 86 35
a

PS and PO refer to the phosphorothioate and phosphodiester internucleoside linkages respectively.

b

ODN sequence d(AGATGTTTGAGCTCT).