Table 1.
Baseline characteristics of participants stratified according to the AST/ALT ratio categories.
| AST/ALT ratio | Total | T1 (≤1.2) | T2 (1.2–1.6) | T3 (≥1.6) | P- value |
| N | 14,220 | 4739 | 4726 | 4755 | |
| Male | 6716 (47.23%) | 2571 (54.25%) | 2064 (43.67%) | 2081 (43.76%) | <.001 |
| Age (yr) | 63.80 ± 9.36 | 59.94 ± 8.75 | 63.79 ± 8.50 | 67.68 ± 9.17 | <.001 |
| Current smoking | 3658 (25.73%) | 1310 (27.65%) | 1124 (23.79%) | 1224 (25.74%) | <.001 |
| Current drinking | 3063 (21.55%) | 1011 (21.35%) | 975 (20.63%) | 1077 (22.65%) | .053 |
| BMI (kg/m2) | 23.61 ± 3.74 | 25.35 ± 3.94 | 23.48 ± 3.25 | 22.00 ± 3.22 | <.001 |
| Mean SBP (mm Hg) | 148.39 ± 17.86 | 147.17 ± 17.04 | 148.67 ± 17.82 | 149.31 ± 18.63 | <.001 |
| Mean DBP (mm Hg) | 88.92 ± 10.75 | 91.02 ± 10.30 | 88.86 ± 10.53 | 86.90 ± 11.01 | <.001 |
| FBG, mmol/L | 6.18 ± 1.61 | 6.63 ± 2.13 | 6.08 ± 1.33 | 5.84 ± 1.07 | <.001 |
| TC, mmol/L | 5.16 ± 1.12 | 5.23 ± 1.17 | 5.18 ± 1.09 | 5.06 ± 1.08 | <.001 |
| TG, mmol/L | 1.81 ± 1.26 | 2.22 ± 1.52 | 1.72 ± 1.10 | 1.48 ± 1.00 | <.001 |
| LDL-C, mmol/L | 2.98 ± 0.81 | 3.11 ± 0.85 | 2.99 ± 0.79 | 2.84 ± 0.79 | <.001 |
| HDL-C, mmol/L | 1.57 ± 0.43 | 1.45 ± 0.37 | 1.58 ± 0.42 | 1.67 ± 0.45 | <.001 |
| TBIL, μmol/L | 14.59 ± 6.85 | 14.96 ± 6.67 | 14.34 ± 6.27 | 14.47 ± 7.53 | <.001 |
| DBIL, μmol/L | 5.55 ± 2.58 | 5.57 ± 2.19 | 5.45 ± 2.17 | 5.64 ± 3.22 | <.001 |
| GGT, U/L | 33.23 ± 43.00 | 44.94 ± 50.45 | 28.35 ± 32.65 | 26.41 ± 41.55 | <.001 |
| ALB, g/L | 46.63 ± 4.05 | 47.23 ± 3.95 | 46.68 ± 3.91 | 45.99 ± 4.20 | <.001 |
| UA, mg/dL | 7.04 ± 2.03 | 7.37 ± 2.08 | 6.89 ± 1.96 | 6.84 ± 2.00 | <.001 |
| HCY, μmol/L | 17.97 ± 11.13 | 17.30 ± 11.30 | 17.73 ± 10.86 | 18.86 ± 11.18 | <.001 |
| eGFR, mL/min/1.73 m2 | 88.18 ± 20.23 | 91.78 ± 19.89 | 88.65 ± 19.56 | 84.12 ± 20.48 | <.001 |
| Medical history, n (%) | |||||
| Diabetes | 2616 (18.40%) | 1328 (28.02%) | 768 (16.25%) | 520 (10.94%) | <.001 |
| Stroke | 981 (6.90%) | 346 (7.30%) | 322 (6.81%) | 313 (6.58%) | .370 |
| CKD | 702 (4.94%) | 236 (4.98%) | 227 (4.80%) | 239 (5.03%) | .870 |
| Dyslipidemia | 2087 (14.68%) | 994 (20.97%) | 640 (13.54%) | 453 (9.53%) | <.001 |
| Medication use, n (%) | |||||
| Antihypertensive drugs | 9218 (64.84%) | 3160 (66.71%) | 3049 (64.53%) | 3009 (63.28%) | .002 |
| Glucose-lowering drugs | 754 (5.30%) | 435 (9.18%) | 206 (4.36%) | 113 (2.38%) | <.001 |
| Lipid-lowering drugs | 504 (3.54%) | 215 (4.54%) | 164 (3.47%) | 125 (2.63%) | <.001 |
| Antiplatelet drugs | 543 (3.82%) | 196 (4.14%) | 180 (3.81%) | 167 (3.51%) | .284 |