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. 2021 Aug 6;100(31):e26805. doi: 10.1097/MD.0000000000026805

Table 5.

Ongoing clinical trials of combination therapy in ASPS.

Trial number Phase Drug Disease Primary endpoint Status completion date
NCT03880123 I Selinexor and Ixazomib Advanced Sarcoma (ASPS) MTD Withdrawn November 2020
NCT01532687 II Gemcitabine Alone or in Combination With Pazopanib Refractory STS (ASPS) PFS Completed October, 2019
NCT02636725 II Concurrent Axitinib and Pembrolizumab Advanced ASPS PFS Active, December, 2022 not recruiting
NCT03989596 II Hypofractionated RT (10x 3.25 Gy) and Deep hyperthermia Unresectable STS (ASPS) Rate of grade 3 Active, December, 2022 not recruiting
NCT03277924 I/II Sunitinib Plus Nivolumab Advanced STS (ASPS) PFSR at 6 months Recruiting September, 2022
NCT04332874 II Pembrolizumab + infusion of melphalan and dactinomycin Advanced ASPS PFS Recruiting April, 2023