Table 3.

Association between OPG polymorphisms and risk of vertebral fracture.

		Heterogeneity		Effect size
Polymorphism	No. of study	I2 (%)	P	OR	95%CI	P
A163G (rs3102735)
G vs A	4	24.9	.262	1.30	1.08–1.58	.006
GG/GA vs AA	5	2.0	.395	1.33	1.07–1.65	.010
GG vs GA/AA	4	0	.485	1.74	1.03–2.92	.037
GG vs AA	4	0	.470	1.85	1.10–3.11	.021
T245G (rs3134069)
G vs T	3	38.0	.199	1.56	1.18–2.05	.002
GG/GT vs TT	4	28.7	.240	1.51	1.15–2.00	.003
GG vs GT/TT	3	0	.895	2.88	1.02–8.13	.046
GG vs TT	3	0	.875	3.07	1.08–8.75	.036
T950C (rs2073617)
C vs T	2	0	.388	0.89	0.72–1.11	.318
CC/CT vs TT	2	0	.952	1.06	0.74–1.53	.736
CC vs CT/TT	2	52.2	.148	0.50	0.13–1.90	.310
CC vs TT	2	33.8	.219	0.79	0.50–1.24	.306
G1181C (rs2073618)
C vs G	4	0	.523	0.99	0.89–1.12	.967
CC/CG vs GG	5	0	.569	1.02	0.86–1.22	.793
CC vs CG/GG	4	67.3	.027	0.96	0.66–1.40	.835
CC vs GG	4	0	.617	1.03	0.82–1.29	.806