Extended Data Figure 12: MEOX1 is expressed in human activated fibroblasts.
a. POSTN (left) and MEOX1 (right) expression in human adult fibroblast clusters (y axis is normalized UMI levels). b. Track showing scATACseq average signal across fibroblasts in the human fetal heart21 in the MEOX1 locus. The syntenic region of Peak9/10 is highlighted in red. c. Bulk RNAseq data of human MEOX1 expression (FPKM) in heart tissue in controls (Ctrl) and individuals with dilated cardiomyopathy (DCM) or hypertrophic cardiomyopathy (HCM) (GSE141910). Unpaired t-test with Benjamini/Hochberg correction. d. Bulk RNAseq data of human MEOX1 expression (raw counts) in lung tissue between controls (Ctrl) and individuals with idiopathic pulmonary fibrosis (GSE134692)22. Unpaired t-test (Two-tailed). c,d, Numbers above figure show significant p-val.