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TOF-SIMS imaging of unwounded skin tissue in positive mode detection. (A) Composite of the m/z channels shown in panels B-D. The m/z of 184 is shown to represent PC headgroup (B). For (C) cholesterol [M-H2O+H]+ ion is shown. Images D and E are constructed as the sum of various channels of the same lipid class, shown in Supplementary Figure S1 and listed in detail in Supplemental Table 1.
