Table 1.
Patient Information. The subjects from the University of Pennsylvania and Mayo Clinic (Rochester) cohorts were labeled as HUP and study, respectively. For each patient, we report sex, as well as age at first reported seizure onset and at phase II monitoring (age). Additionally, we report the seizure etiology, which was clinically determined through medical history, imaging, and long-term invasive monitoring. The different seizures observed (seizure types) include simple-partial (SP), complex-partial (CP), and complex-partial with secondary generalization (CP + GTC). We also indicate the total number of seizures recorded in the epilepsy monitoring unit, as well as the clinical imaging analysis (imaging) that concludes whether the seizure etiology is lesional (L) or non-lesional (NL). Finally, surgical outcome (outcome) was based on either Engel score or ILAE score: seizure freedom to no improvement (I–V), no resection (NR), and no follow-up (NF). Finally, patients are labeled as localizing (L) or non-localizing (NL) based on the localization quality of the seizure onset zone (SOZ localization) after clinical assessment of the iEEG by a board-certified epileptologist (F.M.).
| Patient (IEEG Portal) | sex | Age(Years) (Onset/Surgery) | SeizureOnset | Etiology | Seizure Type | Seizures (N) | Imaging | Outcome | SOZ Localization |
|---|---|---|---|---|---|---|---|---|---|
| HUP64_phaseII | M | 0.3/20 | Left frontal | Dysplasia | CP + GTC | 01 | L | ENGEL-I | L |
| HUP65_phaseII | M | 02/36 | Right temporal | Dysplasia | CP + GTC | 03 | N/A | ENGEL-I | NL |
| HUP68_phaseII | F | 15/26 | Right temporal | Meningitis | CP, CP + GTC | 05 | NL | ENGEL-I | L |
| HUP70_phaseII | M | 10/32 | Left perirolandic | Cryptogenic | SP | 08 | L | NR | L |
| HUP72_phaseII | F | 11/27 | Bilateral left | Mesial temporal sclerosis | CP + GTC | 01 | L | NR | L |
| HUP73_phaseII | M | 11/39 | Anterior right frontal | Meningitis | CP | 05 | NL | ENGEL-I | NL |
| HUP78_phaseII | M | 00/54 | Anterior left temporal | Traumatic injury | CP | 05 | L | ENGEL- III | L |
| HUP79_phaseII | F | 11/39 | Occipital | Meningitis | CP | 01 | L | NR | NL |
| HUP86_phaseII | F | 18/25 | Left temporal | Cryptogenic | CP + GTC | 02 | NL | ENGEL- II | L |
| HUP87_phaseII | M | 21/24 | Frontal | Meningitis | CP | 02 | L | ENGEL-I | NL |
| Study 004–2 | F | 14/27 | Right temporal occipital | Unknown | CP + GTC | 01 | NL | ILAE-IV | NL |
| Study 006 | M | 22/25 | Left frontal | Unknown | CP | 02 | NL | NR | NL |
| Study 010 | F | 00/13 | Left frontal | Neonatal injury | CP + GTC | 02 | L | NF | L |
| Study 011 | F | 10/34 | Right Mesial Frontal | Unknown | CP | 02 | NL | NF | L |
| Study 016 | F | 05/36 | Right temporal orbitofrontal | Unknown | CP + GTC | 03 | NL | ILAE-IV | L |
| Study 019 | F | 31/33 | Left frontal | Unknown | CP + GTC | 15 | NL | ILAE-V | NL |
| Study 020 | M | 05/10 | Right frontal | Unknown | CP + GTC | 04 | NL | ILAE-IV | L |
| Study 023 | M | 01/16 | Left occipital | Unknown | CP | 04 | L | ILAE-I | NL |
| Study 026 | M | 09/09 | Left frontal | Unknown | CP | 10 | NL | ILAE-I | NL |
| Study 031 | M | 05/05 | Right frontal | Unknown | CP + GTC | 05 | NL | NF | NL |
| Study 033 | M | 00/03 | Left frontal | Unknown | GA | 07 | L | ILAE-V | NL |
| Study 037 | F | 45/?? | Indeterminate | Unknown | CP | 02 | NL | NR | NL |