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. 2021 Aug 5;16(8):e0254421. doi: 10.1371/journal.pone.0254421

Fig 7. Frequency of rHA-reactive DN-C in young and elderly participants.

Fig 7

A) Representative gating strategy to quantify rHA-specific DN-C in the peripheral blood of vaccinated participants. B-D) Percentage of vaccine-specific (B), historical-specific (C) and broadly reactive (D) DN-C in young adult (red) and elderly (blue) participants vaccinated for three consecutive years. E-G) Frequency of H1N1 and H3N2 vaccine-specific (E), historical-specific (F), and broadly reactive (G) B-cells in the CS-Bmem or DN-C compartment in young adult and elderly participants 7 days after vaccination.