IC₅₀ values for the inhibition of the binding of FITC-NoxaB to Mcl-1 of small molecules^a.

	Structure	FA IC50 (μM)		Structure	FA IC50 (μM)
1		0.17 [0.15–0.19]	6		3.38 [2.56–4.47]
2		0.36 [0.29–0.45]	7		4.39 [3.95–4.87]
3		0.62 [0.47–0.80]	8		7.03 [6.20–7.97]
4		1.01 [0.89–1.15]	9		>100
5		1.14 [0.84–1.52]	10		>100

^aIC₅₀ values determined by non-linear regression of at least three independent experiments (see ESI). Errors are 95% confidence intervals (CI). Fmoc, 9-fluorenylmethylcarbonyl.