IC50 values for the cell growth inhibition of compounds which demonstrated activity towards pancreatic cancer cell lines, demonstrated by the MTS assaya.
| BxPC3 (μM) | MiaPaCa-2 (μM) | AsPC-1 (μM) | |
|---|---|---|---|
| 1 | 9.16 [5.97–14.88] | 7.20 [6.15–8.45] | 1.73 [1.42–2.14] |
| 2 | 1.48 [1.20–1.87] | 1.12 [1.36–1.94] | 4.401 [3.86–5.02] |
| 3 | 2.74 [1.56–5.00] | 7.09 [5.50–9.09] | >100 μM |
| 4 | 1.35 [1.23–1.49] | 1.14 [1.10–1.19] | >100 μM |
IC50 values determined by non-linear regression of at least three independent experiments (see ESI). Errors are 95% confidence intervals (CI). Table 2: IC50 results obtained for compound 3 and 5 to selected cancerous cell lines in the presence of jacalin or bovine serum albumin (BSA) at 10 μM. Errors are 95% confidence intervals.