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. 2020 Nov 19;2(1):215–219. doi: 10.1039/d0cb00148a

IC50 values for the cell growth inhibition of compounds which demonstrated activity towards pancreatic cancer cell lines, demonstrated by the MTS assaya.

BxPC3 (μM) MiaPaCa-2 (μM) AsPC-1 (μM)
1 9.16 [5.97–14.88] 7.20 [6.15–8.45] 1.73 [1.42–2.14]
2 1.48 [1.20–1.87] 1.12 [1.36–1.94] 4.401 [3.86–5.02]
3 2.74 [1.56–5.00] 7.09 [5.50–9.09] >100 μM
4 1.35 [1.23–1.49] 1.14 [1.10–1.19] >100 μM
a

IC50 values determined by non-linear regression of at least three independent experiments (see ESI). Errors are 95% confidence intervals (CI). Table 2: IC50 results obtained for compound 3 and 5 to selected cancerous cell lines in the presence of jacalin or bovine serum albumin (BSA) at 10 μM. Errors are 95% confidence intervals.