Fig. 3. Thermodynamic profiles (see Fig. S1–S4, ESI†) for the interaction of mannosides 1–4 with FimHLD (A) and FimHFL (B). Data for the interactions FimHLD-2/3/4 and FimHFL-2/4 have been published before.24,30,31 (C) Difference in the thermodynamic profiles between ligand binding to FimHFL and FimHLD. Error bars represent (propagated) 68% confidence intervals. Numeric data and further information can be found in the ESI.†.
