Radiolabeling and quality control of hPep-1-[64Cu] and mPpep-1[64Cu] PET tracers. Radiochemical yield (RCY), molar activity, and radiochemical purity of the as-prepared tracers. Data represent mean ± SD (n = 7).
| Tracers | hPep-1-[64Cu] | mPep-1-[64Cu] |
|---|---|---|
| Radiochemical yield (%) | >90 | >90 |
| Molar activity (GBq μmol−1) | 53.3 ± 4.7 | 55.4 ± 7.3 |
| Radiochemical puritya (%) | >95 | >95 |
| Retention time (tR) | 7.48 min | 7.83 min |
a
The radiochemical purity was determined by HPLC under conditions as follows: YMC-Triat-C18 column (4.6 mm i.d. × 150 mm, 5 μm); solvent gradient of 10–90% acetonitrile (0.1% trifluoroacetic acid (TFA)), 20 min; flow rate of 1 mL min−1.