TABLE 2.

Univariate and multivariate Cox regression analyses in breast cancer using the GSE22220 series dataset.

	Univariate		Multivariate
	HR (95% CI)	P- value	HR (95% CI)	P- value
Age (≥65 vs. < 65)	2.28 (1.42∼3.68)	0.0007	1.81 (1.09–2.99)	0.021
Grade (2–3 vs. 1)	1.82 (1.06∼3.11)	0.030	1.55 (0.89–2.68)	0.118
ER status (1 vs. 0)	0.80 (0.51∼1.26)	0.33
SCCA-CC (multinomial)	0.86 (0.96–1.39)	0.127
PAM50 (multinomial)	1.06 (0.78–1.15)	0.575
SCCA-CC (Class 4 vs. Classes 1–3, 5)	2.95 (1.73∼5.02)	< 0.0001	1.95 (1.07–3.55)	0.030
iCluster (iCluster 5 vs. iCluster 1–4)	2.49 (1.54∼4.02)	0.0002	1.68 (0.97–2.91)	0.063
PAM50 (Her2+ vs. others)	1.77 (0.93∼3.35)	0.08