Antibacterial activities of the different peptides on E. coli D22 strain.

Compound	MICa		MBCb
	μM	μg mL−1	μg mL−1
P 7	>357	>256	n.d.
Onc112	0.21–0.42	0.5–1	1
Onc112-P 7	0.15–0.29	0.5–1	2
Onc112-P 7Scr	0.29–0.58	1–2	2
Py	0.85–3.4	2–8	8
Py-P 7	1.2–2.4	4–8	8
Py-P 7Scr	1.2–4.8	4–16	16
FITC-Py	181–362	512–1024	n.d.
FITC-Py-P7	16.9–33.8	64–128	128
FITC-Py-P7Scr	>269.9	>1024	n.d.
Ampicillin	22.9–45.8	8–16	16
Tetracycline	0.56–1.12	0.25–0.5	0.5

^aRanges of minimal inhibitory concentrations determined in a minimum of 2 independent biological replicates are indicated.

^bMinimal bactericidal concentrations determined in a minimum of 2 independent biological replicates are indicated. See the Experimental section for detailed procedures.