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. 2021 Apr 27;2(4):990–1003. doi: 10.1039/d1cb00038a

Sulfur modifications on nucleobases and phosphate backbone highlighted in this review.

Structure Symbol Modification Location Function
graphic file with name d1cb00038a-u1.jpg S2U 2-thiouridine tRNA U34 wobble position Enhance the Accuracy and efficiency of protein translation
graphic file with name d1cb00038a-u2.jpg S4U 4-thiouridine tRNA U8 Serves as a photo-sensor for near-ultraviolet radiation
graphic file with name d1cb00038a-u3.jpg Ges2U Geranyl-2-thiouridine tRNA U34 Enhance codon recognition and reduce frameshift
graphic file with name d1cb00038a-u4.jpg PS Phosphorothioate Backbone of RNAs Unknown