IC50 (in nM) of small molecule inhibitors against cIAP1/2 and xIAP. Data taken from multiple ref. 55, 115–117.
| cIAP1 | cIAP2 | xIAP | |
|---|---|---|---|
| LCL161 | 0.4 | N/A | 35 |
| Birinapant | 45 | N/A | <1 |
| AZD5582 | 15 | 21 | 15 |
| GDC-0152 | 17 | 43 | 28 |
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