Selection of some of the best enantioselectivities/activities achieved by the artIREDs designs examined in this review. A positive e.e. value reflects selectivity for the (R)-enantiomer, while a negative e.e. reflects selectivity for the (S)-enantiomer14,28,30,34,39,45,48.
| ArIRED | Substrate | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||||||||
| Catalyst loading (mol%) | Conv. (%) | e.e. (%) | Catalyst loading (mol%) | Conv. (%) | e.e. (%) | Catalyst loading (mol%) | Conv. (%) | e.e. (%) | Catalyst loading (mol%) | Conv. (%) | e.e. (%) | Catalyst loading (mol%) | Conv. (%) | e.e. (%) | |
| Streptavidin | 0.025 | Quant. | 96 | 0.5 | 100 | 92 | 0.05 | 100 | 91 | 0.05 | 99 | 96 | |||
| 1 | Quant. | −78 | 0.5 | 99 | −78 | 0.25 | 100 | −25 | 0.5 | 98 | −91 | ||||
| RNase S | 0.49 | 25 | −39 | ||||||||||||
| CAII | 1 | 98 | 74 | ||||||||||||
| 1 | 98 | −94 | 1 | 80 | −75 | ||||||||||
| PBP | 0.25 | 100 | 35 | ||||||||||||