Table 4.
Univariate analysis of overall survival.
| Variable | Mean OS months (95% CI) | P value |
|---|---|---|
| Gender | 0.127 | |
| -Male | 22.73 (16.09-29.38) | |
| -Female | 39.38 (26.62-52.13) | |
| Age at initial diagnosis | 0.162 | |
| ->50 years | 28.74 (20.92-36.55) | |
| -≤50 years | 34.58 (21.92-47.24) | |
| Tumor location | 0.410 | |
| -Cardia | 26.27 (14.77-37.76) | |
| -Noncardia | 32.03 (23.64-40.43) | |
| Tumor cells differentiation | 0.066 | |
| -Poor | 26.49 (14.91-38.06) | |
| -Well/moderate | 32.08 (23.86-40.33) | |
| Lauren classification | 0.014 | |
| -Intestinal | 33.09 (24.95-41.23) | |
| -Diffuse/mixed | 22.19 (11.04-33.34) | |
| History of gastrectomy | 0.030 | |
| -Absent | 33.51 (25.82-41.19) | |
| -Present | 8.59 (2.98-14.19) | |
| History of gastric ulcer | 0.003 | |
| -Absent | 32.26 (24.87-39.64) | |
| -Present | 3.67 (2.34-5.00) | |
| Smoking | 0.674 | |
| -No | 32.04 (23.67-40.41) | |
| -Yes | 23.21 (12.69-33.73) | |
| HER2 immunostaining | 0.956 | |
| -Positive | 18.35 (7.15-29.56) | |
| -Negative | 31.01 (23.48-38.55) | |
| PD-L1 immunostaining | 0.658 | |
| -Positive | 16.39 (5.67-27.11) | |
| -Negative | 25.71 (15.48-35.93) | |
| TCGA classification | <0.001 | |
| -EBV | 7.85 (1.39-14.30) | |
| -MSI | 51.78 (38.59-64.98) | |
| -GS | 15.65 (6.41-24.89) | |
| -CIN | 30.26 (20.71-39.82) | |
| ACRG classification | 0.001 | |
| -MSI | 51.78 (38.59-64.98) | |
| -MSS/EMT | 15.69 (6.82-24.56) | |
| -MSS/P53- | 26.24 (15.27-37.21) | |
| -MSS/P53+ | 25.51 (15.74-35.28) | |
| Integrated classification | <0.001 | |
| -EBV | 7.85 (1.39-14.30) | |
| -MSI | 51.78 (38.59-64.98) | |
| -E-cadherin aberrant | 15.65 (6.41-24.89) | |
| -P53 aberrant | 27.74 (16.26-39.22) | |
| -P53 normal | 26.69 (16.26-37.13) |