Table 3.
Comparison of groups according to TBF test results.
| Parameters | TBF positive (n = 51) | TBF negative (n = 286) | TBF indeterminate (n = 28) | p |
|---|---|---|---|---|
| Sex, n (%) | ||||
| Male | 36 (70.6) | 123 (43.0) | 16 (57.1) | 0.001 ∗ |
| Female | 15 (29.4) | 163 (57.0) | 12 (42.9) | |
|
| ||||
| Age (year), n (%) | ||||
| <30 | 3 (5.9) | 87 (30.4) | 7 (25.0) | ≤0.001 ∗ |
| 31–50 | 18 (35.3) | 131 (45.8) | 11 (39.3) | |
| >50 | 30 (58.8) | 68 (23.8) | 10 (35.7) | |
|
| ||||
| Body mass index, (kg/m2), n (%) | ||||
| Underweight (<18.5 kg/m2) | 2 (3.9) | 41 (14.3) | 6 (21.4) | 0.124 |
| Normal weight (18.5–24.9 kg/m2) | 15 (29.4) | 109 (38.1) | 8 (28.6) | |
| Overweight (24.5–29.9 kg/m2) | 20 (39.2) | 75 (26.3) | 9 (32.1) | |
| Obese (>30 kg/m2) | 14 (27.5) | 61 (21.3) | 5 (17.9) | |
|
| ||||
| Smoking | ||||
| Never smoker, n (%) | 26 (51.0) | 166 (58.0) | 13 (46.4) | 0.124 |
| Former smoker, n (%) | 13 (25.5) | 40 (14.0) | 8 (28.6) | |
| Current smoker, n (%) | 12 (23.5) | 80 (28.0) | 7 (25.0) | |
|
| ||||
| Smoking amount (pack-year), n (%) | ||||
| 0 | 26 (51.0) | 166 (58.0) | 13 (46.4) | 0.003∗ |
| 1–10 | 2 (3.9) | 54 (18.9) | 4 (14.3) | |
| 11–20 | 10 (19.6) | 42 (14.7) | 6 (21.4) | |
| >20 | 13 (25.5) | 24 (18.4) | 5 (17.9) | |
|
| ||||
| TB pass, n (%) | ||||
| Yes | 6 (11.8) | 3 (1.0) | 3 (10.7) | ≤0.001∗ |
| No | 45 (88.2) | 283 (99.0) | 25 (89.3) | |
|
| ||||
| TB subgroup, n (%) | ||||
| Lung TB | 3 (50.0) | 0 (00.0) | 2 (66.7) | 0.138 |
| Extrapulmonary TB | 3 (50.0) | 1 (33.3) | 0 (00.0) | |
| Unknown | 0 (00.0) | 2 (66.7) | 1 (33.3) | |
|
| ||||
| Chronic disease n (%) | ||||
| HT | 11 (21.6) | 24 (8.4) | 5 (17.9) | 0.010 ∗ |
| DM | 4 (7.8) | 23 (8.0) | 5 (17.9) | 0.209 |
| Rheumatologic disease | 27 (52.9) | 137 (47.9) | 10 (35.7) | 0.336 |
| Coronary artery disease | 4 (7.8) | 18 (6.3) | 1 (3.6) | 0.756 |
| Obstructive lung diseases | 4 (7.8) | 18 (6.3) | 1 (3.6) | 0.231 |
| MS | 2 (3.9) | 12 (4.2) | 3 (10.7) | 0.285 |
| Malignancy | 1 (2.0) | 11 (3.8) | 3 (0.7) | 0.154 |
| Hypothyroidism | 2 (3.9) | 12 (4.2) | 2 (7.1) | 0.756 |
| Cardiac arrhythmia | 1 (2.0) | 5 (1.7) | 1 (3.6) | 0.798 |
| IBD | 6 (11.8) | 26 (9.1) | 3 (10.7) | 0.818 |
| CRF | 2 (3.9) | 5 (1.7) | 4 (14.3) | 0.001 ∗ |
|
| ||||
| Drugs used, n (%) | ||||
| Biological treatments | 23 (45.1) | 137 (47.9) | 9 (32.1) | 0.275 |
| Corticosteroid | 16 (31.4) | 105 (36.7) | 9 (32.1) | 0.705 |
|
| ||||
| COVID-19 status, n (%) | ||||
| Passed (PCR positive) | 6 (11.8) | 31 (10.8) | 9 (32.1) | 0.005 ∗ |
|
| ||||
| Weight of patients with COVID-19, n (%) | ||||
| Outpatient treatment | 4 (66.7) | 22 (71.0) | 6 (66.7) | 0.950 |
| Treatment in the hospital | 2 (33.3) | 9 (29.0) | 3 (33.3) | |
| Intensive care treatment | 0 (00.0) | 0 (00.0) | 0 (00.0) | |
|
| ||||
| COVID-19 vaccine status, n (%) | ||||
| Done | 10 (19.6) | 37 (12.9) | 3 (10.7) | 0.395 |
| Not done | 41 (80.4) | 249 (87.1) | 25 (89.3) | |
CRF: chronic renal failure; DM: diabetes mellitus; HT: hypertension; IBD: inflammatory bowel disease; MS: multiple sclerosis; TBF: Standard ETB-Feron ELISA (TBF) test. ∗p value < 0.05 was considered statistically significant. Values below 0.05 are in bold and indicate statistically significant differences between two categories.