Table 13.
Rat/mouse cells: cellular response (presence or absence) for cultured rat/mouse cells.
| No. | Cell line | Frequency and intensity | Cell response analysis | Result | Year | Authors |
|---|---|---|---|---|---|---|
| 79 | The murine osteoblast-like cell line MC3T3-E1 | Frequency of 0.5 Hz, intensities of 0.17 mT and 1.33 mT | Cell proliferation Cell differentiation Gene expression Protein expression |
The proliferation and differentiation of cells in PEMF exposure groups changed, COL-I and Cbfa1 mRNA expression and BMP2/4 and Smad1/5/8 protein expression did not change. | 2011 | Li et al. [93] |
| 80 | Rat basophilic leukemia cells (RBL-2H3) | Frequency of 8 kHz, intensity of 200 mT | Cell morphology Cell proliferation Gene expression |
PEMF Stimulation led to increased cell proliferation |
2010 | Choi et al. [97] |
| 81 | Rat bone marrow cells | Frequency of 8 Hz, intensity of 3.8 mT | Gene expression | No statistically significant difference was found between the PEMF group and the control group | 2010 | Chen et al. [98] |
| 82 | Neural stem cells (NSCs) | Frequency of 0.1 Hz, intensities of 0.5, 1.0, 3.0, 4.0, 5.0, 6.0, 8.0, and 10.0 T | Cell proliferation Cell differentiation |
Exposure of NSCs to PEMFs changed cell proliferation | 2009 | Meng et al. [77] |
| 83 | Osteoblast-like MC3T3-E1 cells Primary osteoblast cells |
Frequency of 48 Hz Intensity of 1.55 mT |
Cell proliferation Cell differentiation |
PEMF treatment accelerated the cell proliferation and promoted cell differentiation of the primary osteoblast cell. | 2008 | Wei et al. [87] |
| 84 | Rat primary osteoblastic cells | Frequency of 3.8 kHz | Cell proliferation Gene expression |
Continuous daily 4 h treatment with PEMF alone increased expression of osteoblast marker genes | 2007 | Selvamurugan et al. [88] |
| 85 | A rat osteogenic cell line | Physio-stim® PEMF signals | Signal pathway | PEMF induced rapid phosphorylation reactions of Intracellular signaling molecules | 2006 | Schnoke and Midura [89] |
| 86 | Murine Preosteoblasts MC3T3-E1 Fibroblast cell lines |
Frequency of 3850 Hz Intensity of 0.4 mT |
Signal transduction pathway | mTOR pathway was activated within minutes of PEMF exposure | 2006 | Patterson et al. [95] |