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. 2021 Jul 29;2021:6647497. doi: 10.1155/2021/6647497

Table 13.

Rat/mouse cells: cellular response (presence or absence) for cultured rat/mouse cells.

No. Cell line Frequency and intensity Cell response analysis Result Year Authors
79 The murine osteoblast-like cell line MC3T3-E1 Frequency of 0.5 Hz, intensities of 0.17 mT and 1.33 mT Cell proliferation
Cell differentiation
Gene expression
Protein expression
The proliferation and differentiation of cells in PEMF exposure groups changed, COL-I and Cbfa1 mRNA expression and BMP2/4 and Smad1/5/8 protein expression did not change. 2011 Li et al. [93]
80 Rat basophilic leukemia cells (RBL-2H3) Frequency of 8 kHz, intensity of 200 mT Cell morphology
Cell proliferation
Gene expression
PEMF
Stimulation led to increased cell proliferation
2010 Choi et al. [97]
81 Rat bone marrow cells Frequency of 8 Hz, intensity of 3.8 mT Gene expression No statistically significant difference was found between the PEMF group and the control group 2010 Chen et al. [98]
82 Neural stem cells (NSCs) Frequency of 0.1 Hz, intensities of 0.5, 1.0, 3.0, 4.0, 5.0, 6.0, 8.0, and 10.0 T Cell proliferation
Cell differentiation
Exposure of NSCs to PEMFs changed cell proliferation 2009 Meng et al. [77]
83 Osteoblast-like MC3T3-E1 cells
Primary osteoblast cells
Frequency of 48 Hz
Intensity of 1.55 mT
Cell proliferation
Cell differentiation
PEMF treatment accelerated the cell proliferation and promoted cell differentiation of the primary osteoblast cell. 2008 Wei et al. [87]
84 Rat primary osteoblastic cells Frequency of 3.8 kHz Cell proliferation
Gene expression
Continuous daily 4 h treatment with PEMF alone increased expression of osteoblast marker genes 2007 Selvamurugan et al. [88]
85 A rat osteogenic cell line Physio-stim® PEMF signals Signal pathway PEMF induced rapid phosphorylation reactions of Intracellular signaling molecules 2006 Schnoke and Midura [89]
86 Murine
Preosteoblasts
MC3T3-E1
Fibroblast cell lines
Frequency of 3850 Hz
Intensity of 0.4 mT
Signal transduction pathway mTOR pathway was activated within minutes of PEMF exposure 2006 Patterson et al. [95]