Table 2.
Carrier nanoparticle material | Imaging agent and Imaging modality | Therapeutics/drugs | Target markers | Binding ligand | Ref. |
---|---|---|---|---|---|
Iron oxide nanoparticles | Iron oxide - MRI | rtPA | N/A | N/A | 77 |
Iron oxide nanoparticles | Iron oxide - SPECT/CT | rtPA | N/A | N/A | 78 |
Iron oxide nanoparticles | Iron oxide - MRI | rtPA | Platelet membrane glycoprotein GP IIb//IIIa | RGD peptides | 79 |
Iron oxide nanoparticles | Iron oxide - MRI/ VT680 - Fluorescence | rtPA | Activated factor XIII | Activated factor XIII sensitive peptide (FXIIIa) GNQEQVSPLTLLKC | 85 |
Perfluorocarbon polymer nanoparticles | Perfluorocarbon - MRI | PPACK | Thrombin | PPACK | 88-90 |
borylbenzyl carbonate nanoparticles | IR780/IR820 - NIR | hydroxybenzyl alcohol (HBA) | Fibrin | GPRPP- pentapeptide | 91, 92 |