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. 2021 Jul 21;5(4):499–514. doi: 10.7150/ntno.62730

Table 2.

Theranostic nanoparticles for thrombotic diseases.

Carrier nanoparticle material Imaging agent and Imaging modality Therapeutics/drugs Target markers Binding ligand Ref.
Iron oxide nanoparticles Iron oxide - MRI rtPA N/A N/A 77
Iron oxide nanoparticles Iron oxide - SPECT/CT rtPA N/A N/A 78
Iron oxide nanoparticles Iron oxide - MRI rtPA Platelet membrane glycoprotein GP IIb//IIIa RGD peptides 79
Iron oxide nanoparticles Iron oxide - MRI/ VT680 - Fluorescence rtPA Activated factor XIII Activated factor XIII sensitive peptide (FXIIIa) GNQEQVSPLTLLKC 85
Perfluorocarbon polymer nanoparticles Perfluorocarbon - MRI PPACK Thrombin PPACK 88-90
borylbenzyl carbonate nanoparticles IR780/IR820 - NIR hydroxybenzyl alcohol (HBA) Fibrin GPRPP- pentapeptide 91, 92