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. 2021 Jul 21;5(4):499–514. doi: 10.7150/ntno.62730

Table 4.

Theranostic nanoparticles for injured arteries.

Carrier Nanoparticle material Imaging agent and imaging modality Therapeutics/drugs Target Binding ligand Disease Ref.
Iron oxide nanoparticles Iron oxide- MRI Endothelial cell Arterial stent Magnetic target Injured arteries after stent, lack of reendothelization 121
Perfluorocarbon nanomaterials Perfluorocarbon - MRI Doxorubicin and paclitaxel Smooth muscle cell membranes Tissue factor In-stent restenosis 122
Perfluorocarbon nanoparticles Perfluorocarbon - MRI Rapamycin Vitronectin on the injured vessel wall avb3-integrin Vascular injury; in-stent restenosis 123