Table 4.
Theranostic nanoparticles for injured arteries.
Carrier Nanoparticle material | Imaging agent and imaging modality | Therapeutics/drugs | Target | Binding ligand | Disease | Ref. |
---|---|---|---|---|---|---|
Iron oxide nanoparticles | Iron oxide- MRI | Endothelial cell | Arterial stent | Magnetic target | Injured arteries after stent, lack of reendothelization | 121 |
Perfluorocarbon nanomaterials | Perfluorocarbon - MRI | Doxorubicin and paclitaxel | Smooth muscle cell membranes | Tissue factor | In-stent restenosis | 122 |
Perfluorocarbon nanoparticles | Perfluorocarbon - MRI | Rapamycin | Vitronectin on the injured vessel wall | avb3-integrin | Vascular injury; in-stent restenosis | 123 |