Table 1.
Incidence rates, hazard ratio, and 95% CI of COVID-19 hospitalisation, mortality, and vaccination among schizophrenia patients and controls within 1 year follow-up
|
Hospitalisation |
Mortality |
Vaccination |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | Control | p value | Schizophrenia | Control | p value | Schizophrenia | Control | p value | |
| Follow-up time, person-years | 25 257 | 25 487 | .. | 25 443 | 25 511 | .. | 5305 | 4880 | .. |
| Number of events | 298 | 58 | .. | 100 | 33 | .. | 12 928 | 14 472 | .. |
| Incidence rate per 1000 person-years (95% CI) | 11·79 (10·52–13·20) | 2·27 (1·74–2·92) | .. | 3·93 (3·21–4·76) | 1·29 (0·90–1·79) | .. | 2436·96 (2395·82–2478·81) | 2965·57 (2918·37–3013·56) | .. |
| Unadjusted HR (95% CI) | 5·16 (3·89–6·83) | Ref | p<0·0001 | 3·03 (2·04–4·49) | Ref | p<0·0001 | 0·83 (0·81–0·85) | Ref | p<0·0001 |
| HR adjusted for demographic factors* (95% CI) | 4·58 (3·40–6·16) | Ref | p<0·0001 | 2·48 (1·62–3·77) | Ref | p<0·0002 | 0·85 (0·83–0·87) | Ref | p<0·0001 |
| HR adjusted for clinical factors† (95% CI) | 4·81 (3·57–6·48) | Ref | p<0·0001 | 2·52 (1·64–3·85) | Ref | p<0·0002 | 0·83 (0·81–0·85) | Ref | p<0·0001 |
For people with schizophrenia group, n=25 539 and for the control group, n=25 539.
Adjusted for age, sex, marital status, population group, and socioeconomic status.
Adjusted for diabetes, hypertension, asthma, hyperlipidaemia, chronic obstructive pulmonary disease, ischaemic heart disease, smoking, and obesity.