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. 2021 Jun 14;25(8):4801–4815. doi: 10.1007/s00784-021-04024-1

Table 3.

Bivariate diagnostic random-effects meta-analysis for the finally included in vitro studies for all diagnostic methods at different caries detection levels

Meta-analytical diagnostic performance In vitro
Caries detection level Dentin detection level 1/3 dentin detection level
VE N
SE (95% CI)
SP (95% CI)
AUC (Reitsma)
DOR
3
0.59 (0.52–0.67)
0.83 (0.70–0.92)
0.59
5.55 (1.88–16.38)
8
0.46 (0.20–0.73)
0.87 (0.72–0.95)
0.79
5.93 (3.11–11.31)
2
0.69 (0.51–0.82)
0.88 (0.83–0.92)
0.89
16.6 (4.85–56.79)
Conventional bitewing radiography (D-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

-

1

0.42 (0.18–0.69)

0.73 (0.53–0.87)

0.60

1.94 (0.46–8.17)

-
Conventional bitewing radiography (E-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

-

2

0.48 (0.21–0.77)

0.95 (0.53–0.997)

0.75

10.69 (3.67–31.15)

-
Conventional bitewing radiography (F-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

-

2

0.50 (0.22–0.79)

0.97 (0.71–0.998)

0.82

23.60 (8.28–67.24)

-
Digital bitewing radiography (phosphor plates)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

-

2

0.48 (0.24–0.73)

0.95 (0.59–0.995)

0.73

15.57 (0.47–515.27)

-
LF 2095

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

6

0.75 (0.58–0.86)

0.76 (0.60–0.87)

0.81

10.28 (4.35–24.28)

7

0.68 (0.54–0.79)

0.78 (0.68–0.85)

0.79

8.01 (4.04–15.88)

-
LF pen 2190

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

2

0.78 (0.44–0.94)

0.77 (0.62–0.87)

0.77

11.83 (2.66–52.63)

4

0.63 (0.37–0.83)

0.77 (0.62–0.88)

0.78

5.85 (1.77–19.30)

-
Fibre-optic transillumination FOTI

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

1

0.97 (− 0.92–0.99)

0.50 (0.34–0.66)

0.92

38.33 (10.15–144.77)

2

0.49 (0.20–0.79)

0.97 (0.89–0.994)

0.92

37.77 (13.69–104.19)

-