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. 2021 Jun 14;25(8):4801–4815. doi: 10.1007/s00784-021-04024-1

Table 4.

Bivariate diagnostic random-effects meta-analysis for the finally included in vivo studies for all diagnostic methods at different caries detection levels

Meta-analytical diagnostic performance In vivo
Caries detection level Dentin detection level 1/3 dentin detection level
VE N
SE (95% CI)
SP (95% CI)
AUC (Reitsma)
DOR
2
0.70 (0.59 − 0.80)
0.47 (0.26 − 0.70)
0.70
2.14 (0.73 − 6.28)
- 3
0.72 (0.52 − 0.86)
0.77 (0.67 − 0.85)
0.77
10.18 (3.94 − 26.29)
Conventional bitewing radiography (D-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

1

0.65 (0.57 − 0.73)

0.58 (0.42 − 0.72)

0.65

2.59 (1.24 − 5.44)

2

0.79 (0.41 − 0.96)

0.75 (0.68 − 0.82)

0.77

11.79 (2.43 − 57.24)

-
Conventional bitewing radiography (E-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

1

0.80 (0.71 − 0.87)

0.94 (0.46 − 0.996)

0.94

60.37 (3.31v1100.70)

2

0.76 (0.61 − 0.87)

0.98 (0.79 − 0.998)

0.90

127.56 (7.38 − 2203.70)

-
Conventional bitewing radiography (F-speed)

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

- - -
Digital bitewing radiography

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

- - -
LF 2095

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

1

0.88 (0.81 − 0.93)

0.71 (0.55 − 0.83)

0.88

18.33 (7.57 − 44.37)

2

0.91 (0.86 − 0.95)

0.78 (0.46 − 0.94)

0.92

35.90 (13.43 − 96.00)

-
LF pen 2190

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

- - -
Fibre-optic transillumination FOTI

N

SE (95% CI)

SP (95% CI)

AUC (Reitsma)

DOR

- - -