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. 2021 Aug 5;11:15862. doi: 10.1038/s41598-021-95413-9

Table 1.

Demographics of the study participants (n = 69).

Clinical parameters
Age (years) 71.1 ± 9.0
Gender (male/female) 66/3
BMI (kg/m2) 21.4 ± 3.8
Smoking history (pack-year) 67.6 ± 33.0
GOLD stage (I/II/III/IV, n) 12/27/25/5
mMRC dyspnea scale (0/1/2/3/4, n) 5/18/27/16/3
COPD assessment test (n = 41) 16.8 ± 7.6
6-min walk distance (n = 48) (m) 386.1 ± 115.8
Medications
No respiratory medication, n (%) 5 (7.2%)
LAMA or LABA alone, n (%) 17 (24.6%)
LABA-LAMA combo, n (%) 19 (27.5%)
ICS-LABA combo, n (%) 9 (13.0%)
Triple combo, n (%) 19 (27.5%)
Pulmonary function
%VC (%) 100.4 ± 18.4
%FVC (%) 95.2 ± 17.5
FEV1 (L) 1.35 ± 0.59
FEV1/FVC (%) 43.8 ± 13.4
%FEV1 (%) 60.2 ± 24.2
DLco (%) 65.9 ± 24.3
Evaluation of skeletal muscle on CT (n = 56)
PMCSA (cm2) 25.9 ± 7.9
ECMCSA (cm2) 27.8 ± 6.2

BMI body mass index, GOLD global initiative for chronic obstructive lung disease, mMRC modified medical research council, COPD chronic obstructive pulmonary disease, LAMA long-acting muscarinic antagonist, LABA long acting β2 adrenergic agonist, ICS inhaled corticosteroid, VC vital capacity, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, DLco diffusing capacity of lung for carbon monoxide, PMCSA cross-sectional area of pectoralis muscles, ECMCSA cross-sectional area of erector spinae muscles. Data are presented as mean ± standard deviation.