Table 1.
Open brainlife.io web services and containerized applications implementing the processing pipeline developed for the current work.
| App name | App purpose | DOI |
|---|---|---|
| AC-PC Alignment of T1 | Align T1w anatomical images along the AC-PC plane | bl.app.99 |
| AC-PC Alignment of T2 | Align T2w anatomical images along the AC-PC plane | bl.app.116 |
| FreeSurfer (v6.0.0) | Create surfaces and cortical labels | bl.app.0 |
| dMRI Preprocessing | Correct dMRI data of artifacts and align to T1w image | bl.app.68 |
| RACE-Track (Tractography) | Create an anatomically constrained whole-brain ensemble tractogram | bl.app.101 |
| Multi-Atlas Transfer Tool (maTT) | Map HCP-MMP atlas to individual subjects’ brains | bl.app.23 |
| Network Construction | Create networks from tractography and cortical labels | bl.app.121 |
We developed a computationally reproducible data processing pipeline utilizing the cloud computing platform brainlife.io89. Each step within the pipeline is briefly described and available for download as a Docker138 container run via Singularity139. Each step of the pipeline is also publicly shared as an App (web service) on the brainlife.io platform. brainlife.io Apps can be freely executed on public or private computing resources. All processed brain imaging data and Apps are accessible in a single record as a brainlife.io publication at89.