. 2021 Aug 5;11:15892. doi: 10.1038/s41598-021-95158-5

Table 1.

Ratings of constipation.

Groups	Total	Sampling	Evaluation time (after surgery or enrol)	Defecation rate		Number of faecal particles		Bristol stool scale
Groups	Total	Sampling	Evaluation time (after surgery or enrol)	2-h (%)	24-h (%)	2-h	24-h	1–2	3–4	5–7
Intact rats	n = 18	n = 12	3 days	42	100	4.8 ± 2.0	48.9 ± 10.9	0	13	2
			2 weeks	44	100	4.6 ± 2.2	49.9 ± 11.6	2	12	2
			4 weeks	39	100	4.5 ± 2.3	40.2 ± 8.9	0	13	1
			12 weeks	44	100	4.7 ± 3.0	47.7 ± 10.1	1	14	1
				42	100	4.7 ± 2.8	46.7 ± 9.1
Rats with S	n = 18	n = 12	3 days	33	100	4.2 ± 2.1	44.9 ± 11.9	0	6	6
			2 weeks	42	100	4.7 ± 2.4	49.9 ± 9.9	0	15	0
			4 weeks	42	100	4.3 ± 2.7	47.3 ± 12.9	0	14	1
			12 weeks	44	100	5.0 ± 3.1	48.9 ± 8.9	1	13	2
				40.2^‡§	100	4.5 ± 2.9^‡	47.7 ± 10.9	^‡§	^‡§
SCI rats	n = 18	n = 10	3 days	64	100	2.6 ± 1.7	43.6 ± 11.5	10	10	3
			2 weeks	81	100	2.8 ± 1.3	45.7 ± 13.5	19	8	2
			4 weeks	69	100	2.3 ± 1.1	41.3 ± 9.5	15	8	2
			12 weeks	75	100	2.4 ± 1.2	40.2 ± 12.5	17	9	1
				72^†	100	2.5 ± 1.2^†	42.7 ± 12.1	^†	^†
SCI rats with S	n = 18	n = 10	3 days	50	100	4.5 ± 2.1	43.6 ± 11.5	4	12	2
			2 weeks	61	100	4.2 ± 2.1	42.6 ± 12.8	6	14	2
			4 weeks	61	100	3.9 ± 1.8	41.9 ± 9.5	6	12	4
			12 weeks	56	100	4.3 ± 1.9	40.6 ± 11.0	8	12	0
				57**	100	4.2 ± 1.9*	42.1 ± 11.3	**	**

Defecation rate, the percentage of defecation rats during a given period. Bold type, the average of the four time points. *p < 0.05, comparison between SCI Rats with S and SCI Rats; **p < 0.05, between SCI Rats with S and Intact rats; ^†p < 0.05, between SCI Rats and Intact Rats; ^‡p < 0.05, between Rats with S and SCI Rats; ^§P < 0.05, between Rats with S and SCI Rats with S (Chi-square test or two-way ANOVA).