Table 3.

Multiple backward stepwise regression analysis for ABI and CIMT as dependent variables.

	Adjusted R2	β	Standard error	t	P
ABI	0.537				< 0.0001
Current smokers		− 0.206	0.019	− 2.735	0.0075
Diabetes mellitus		− 0.163	0.017	− 2.342	0.0212
Serum IL6 (pg/mL)		− 0.288	0.003	− 3.454	0.00083
Serum Klotho (pg/mL)		0.236	0.000052	2.841	0.0055
PBCs KL mRNA (a.u.)		0.238	0.013	2.963	0.0037
CIMT	0.370				< 0.0001
Serum IL6 (pg/mL)		0.229	0.139	2.391	0.019
Serum Klotho (pg/mL)		− 0.366	0.000238	− 3.887	< 0.001
PBCs KL mRNA (a.u.)		− 0.171	0.0595	− 1.885	0.041

ABI ankle-brachial index, CIMT carotid intima-media thickness, PBCs peripheral blood cells, IL interleukin, KL Klotho gene.