Table 1.
Clinical characteristics of participants.
| Patients with LLD | Healthy controls | Statistical values | p-value | |
|---|---|---|---|---|
| Number | 48 | 52 | ||
| Age, years (mean, SD) | 74.1 (7.5) | 72.4 (6.4) | t = 1.2, df = 98 | 0.21 |
| Female, n (%) | 33 (68.5%) | 37 (71.2%) | χ2 = 0.07, df = 1 | 0.79 |
| ApoE 4 carrier, n (%) | 12 (25.0%) | 22 (42.3%) | χ2 = 3.08, df = 1 | 0.08 |
| Psychotic depression, n (%) | 16 (33.3%) | |||
| Late-onset depression, n (%) | 28 (58.3%) | |||
| Geriatric Depression Scale (mean, SD) | 23.1 (4.3) | 3.0 (3.1) | t = 24.4, df = 80 | < 0.001 |
| Episodic memory domain scores (mean, SD) | − 3.8 (3.0) | 0 (2.7) | t = 6.4, df = 90 | < 0.001 |
SD standard deviation.