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. 2021 Apr 30;26(8):e1320–e1326. doi: 10.1002/onco.13778
Number of Patients, Male 26
Number of Patients, Female 18
Stage Eligibility required pathologic diagnosis confirming metastatic and unresectable colorectal adenocarcinoma
Age Median (range): 52 (25–76) years
Number of Prior Systemic Therapies Median (range): 2 (2–3)
Performance Status: ECOG

0 — 15

1 — 24

2 — 5

3 — 0

Unknown — 0

Other

Primary site of disease: right side, 8; left side, 36.

Differentiation of tumors: poor, 4; moderate or well, 30; unknown, 10.

Prior targeted therapy: cetuximab, 9; bevacizumab, 29.

KRAS/NRAS/BRAF status: KRAS mutation, 23; NRAS mutation, 3; BRAF mutation, 2; Unknown, 7.

Cancer Types or Histologic Subtypes Colorectal adenocarcinoma, 44