| All Cycles | |||||||
|---|---|---|---|---|---|---|---|
| Name | NC/NA, % | Grade 1, % | Grade 2, % | Grade 3, % | Grade 4, % | Grade 5, % | All grades, % |
| Anemia | 52 | 30 | 14 | 5 | 0 | 0 | 48 |
| AST, SGOT | 59 | 25 | 11 | 5 | 0 | 0 | 41 |
| ALT, SGPT | 68 | 23 | 9 | 0 | 0 | 0 | 32 |
| Leukocytes (total WBC) | 68 | 16 | 11 | 5 | 0 | 0 | 32 |
| Hypoalbuminemia | 75 | 16 | 9 | 0 | 0 | 0 | 25 |
| Neutrophils/granulocytes (ANC/AGC) | 80 | 11 | 7 | 2 | 0 | 0 | 20 |
| Platelets | 80 | 14 | 5 | 2 | 0 | 0 | 20 |
| Proteinuria | 84 | 11 | 5 | 0 | 0 | 0 | 16 |
| Bilirubin (hyperbilirubinemia) | 91 | 5 | 0 | 5 | 0 | 0 | 9 |
| Anorexia | 64 | 32 | 5 | 0 | 0 | 0 | 36 |
| Diarrhea | 73 | 18 | 7 | 2 | 0 | 0 | 27 |
| Fatigue | 84 | 16 | 0 | 0 | 0 | 0 | 16 |
| Vomiting | 84 | 14 | 2 | 0 | 0 | 0 | 16 |
| Petechiae/purpura (hemorrhage/bleeding into skin or mucosa) | 70 | 30 | 0 | 0 | 0 | 0 | 30 |
| Hypertension | 82 | 16 | 2 | 0 | 0 | 0 | 18 |
| Hyperpigmentation | 59 | 25 | 16 | 0 | 0 | 0 | 41 |
| Pruritus/itching | 86 | 9 | 2 | 2 | 0 | 0 | 14 |
Abbreviations: AGC, absolute granulocyte count; ALT, alanine aminotransferase; ANC, absolute neutrophil count; AST, aspartate transaminase; NC/NA, no change from baseline/no adverse event; SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic pyruvic transaminase; WBC, white blood cell.