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. 2021 Jun 5;26(8):e1406–e1417. doi: 10.1002/onco.13841

Table 2.

Cost estimation approach and inputs for studies estimating the cost of multiple steps in the breast cancer care pathway

Costing characteristics Reviewed studies (n = 33) a
Costing approach
Micro 22 (67)
Gross 5 (15)
Micro + gross 6 (18)
Sources for costs and resource use
Patients (e.g., interviews, questionnaires) 14 (42)
Medical records 13 (39)
Hospital finance/administrative data 16 (48)
Government data 16 (48)
Insurance data 4 (12)
Literature 8 (24)
Expert opinion 10 (30)
Cost categories included
Direct medical 33 (100)
Direct nonmedical 9 (27)
Indirect 7 (21)
Inputs into direct medical costs b 33 (100)
Medical visits 25 (76)
Diagnostic studies/pathology 23 (70)
Tumor‐directed medications 30 (91)
Supportive medications 13 (39)
Surgery 27 (82)
Radiotherapy 22 (67)
Hospitalization 26 (79)
Imaging 14 (42)
Laboratory tests and blood services (electrolytes, urinalysis, complete blood count) 22 (67)
Palliative care 10 (30)
Training 4 (12)
Administrative/overhead costs 9 (27)
Unspecified medical costs 4 (12)
Inputs into direct nonmedical costs b , c 9 (100)
Food 7 (78)
Travel/Transportation 9 (100)
Accommodation 5 (56)
Food, transportation, or accommodation for companion 2 (22)
Other (e.g., child tutoring, home help) 1 (11)
Inputs into indirect costs b , c 7 (100)
Lost wages from cancer care 7 (100)
Lost wages from disability/premature mortality 6 (86)
Lost wages of companion 5 (71)

Data are presented as n (%).

a

Data from the 33 studies that estimate the cost of multiple steps in the breast cancer care pathway.

b

Categories are not mutually exclusive, and percentages may sum up to more than 100%.

c

Inputs into direct medical costs, n = 33; inputs into direct nonmedical costs, n = 9; inputs into indirect costs, n = 7.