Table 4.
Differences in depression, anxiety, and distress between MCA and standard oncological care
| Mood scale | MCA intervention | Standard oncological care | p value |
|---|---|---|---|
| PHQ‐4 sum score | |||
| t0 | |||
| n | 79 | 74 | |
| Mean ± SD | 4.1 ± 3.1 | 5.0 ± 3.4 | .129 a |
| t1 | |||
| n | 50 | 50 | |
| Mean ± SD | 3.5 ± 2.9 | 3.9 ± 2.9 | .565 b |
| t2 | |||
| n | 43 | 40 | |
| Mean ± SD | 3.4 ± 2.9 | 4.1 ± 3.1 | .724 b |
| t3 | |||
| n | 31 | 36 | |
| Mean ± SD | 4.2 ± 3.6 | 3.6 ± 3.1 | .284 b |
| PHQ‐2 sum score | |||
| t0 | |||
| n | 79 | 74 | |
| Mean ± SD | 2.0 ± 1.5 | 2.6 ± 1.6 | .041 a |
| ≥3, n (%) | 26 (32.9) | 31 (41.9) | .251 c |
| t1 | |||
| n | 50 | 50 | |
| Mean ± SD | 1.8 ± 1.6 | 1.9 ± 1.4 | .421 b |
| ≥3, n (%) | 12 (24.0) | 13 (26.0) | .446 d |
| t2 | |||
| n | 43 | 40 | |
| Mean ± SD | 1.7 ± 1.4 | 2.1 ± 1.6 | .555 b |
| ≥3 n (%) | 7 (16.3) | 15 (37.5) | .236 d |
| t3 | |||
| n | 31 | 36 | |
| Mean ± SD | 2.1 ± 1.8 | 2.0 ± 1.6 | .256 b |
| ≥3, n (%) | 10 (32.3) | 12 (33.3) | .867 d |
| GAD‐2 sum score | |||
| t0 | |||
| n | 79 | 74 | |
| Mean ± SD | 2.1 ± 1.8 | 2.4 ± 2.0 | .361 a |
| ≥3 n (%) | 28 (35.4) | 28 (37.8) | .759 c |
| t1 | |||
| n | 50 | 50 | |
| Mean ± SD | 1.7 ± 1.5 | 2.1 ± 1.8 | .814 b |
| ≥3, n (%) | 9 (18.0) | 15 (30.0) | .833 d |
| t2 | |||
| n | 43 | 41 | |
| Mean ± SD | 1.7 ± 1.7 | 1.9 ± 1.7 | .889 b |
| ≥3, n (%) | 7 (16.3) | 11 (26.8) | .964 d |
| t3 | |||
| n | 31 | 36 | |
| Mean ± SD | 2.1 ± 1.9 | 1.6 ± 1.6 | .300 b |
| ≥3, n (%) | 10 (32.3) | 8 (22.2) | .120 d |
| Distress Thermometer | |||
| t0 | |||
| n | 72 | 74 | |
| Mean ± SD | 5.9 ± 2.4 | 6.3 ± 2.6 | .416 a |
| ≥5, n (%) | 55 (76.4) | 50 (67.6) | .236 c |
| t1 | |||
| n | 51 | 46 | |
| Mean ± SD | 4.9 ± 2.5 | 5.5 ± 2.4 | .146 b |
| ≥5, n (%) | 33 (64.7) | 31 (67.4) | .357 d |
| t2 | |||
| n | 38 | 38 | |
| Mean ± SD | 5.2 ± 2.7 | 4.7 ± 2.6 | .309 b |
| ≥5, n (%) | 26 (68.4) | 21 (55.3) | .551 d |
| t3 | |||
| n | 27 | 36 | |
| Mean ± SD | 5.8 ± 3.2 | 5.2 ± 2.6 | .473 b |
| ≥5, n (%) | 17 (63.0) | 23 (63.9) | .837 d |
a
Mann‐Whitney U test.
b
Linear model with adjustment for baseline value.
c
Chi‐square independence test.
d
Logistic regression with adjustment for baseline value.
Abbreviations: GAD‐2, Generalized Anxiety Disorder two‐item questionnaire; MCA, Milestone Communication Approach; PHQ‐2, Patient Health Questionnaire (two depression items); PHQ‐4, Patient Health Questionnaire for Depression and Anxiety (PHQ‐2 and GAD‐2); t0, baseline assessment; t1, 3‐month follow‐up; t2, 6‐month follow‐up; t3, 12‐month follow‐up.