Table 1.
List of Basal Insulin Analogues Included in the Review
| Insulin class | Insulin origin | Insulin class (Origin), frequency | Generic names | Brand names |
|---|---|---|---|---|
| Intermediate-acting | Animal | Intermediate-acting (animal), od |
NPH (Isophane insulin); Lente (Zinc insulin) |
Iletin II, Insulatard MC; Monotard MC |
| Intermediate-acting (animal), bid | ||||
| Intermediate-acting (animal), NR | ||||
| Animal/human | Intermediate-acting (animal and human), bid | NPH (isophane insulin) | - | |
| Human | Intermediate-acting (human), od |
NPH (Isophane insulin); Lente (Zinc insulin) |
Humulin N, Novolin N, Protaphane HM; Novolin L, Humulin L, Monotard HM |
|
| Intermediate-acting (human), bid | ||||
| Intermediate-acting (human), qid | ||||
| Intermediate-acting (human), NR | ||||
| Long-acting | Human | Long-acting (human), od | Detemir; Glargine |
Levemir; Lantus |
| Long-acting (human), bid | ||||
| Biosimilar | Long-acting (biosimilar), od | Glargine | Basaglar (or Abasaglar), LY2963016, MYL-1501D, Toujeo | |
| Ultra-long-acting | Human | Ultra-long-acting (human), od | Degludec | Tresiba |
Abbreviations: bid, twice a day; NPH, neutral protamine Hagedorn; NR, not reported; od, once a day; qid, four times a day