Table 3.
Measures of gray matter volume and density in habit or goal-directed circuits’ regions.
Adult AN | Adult HC | P | Adolescent AN | Adolescent HC | P | |
---|---|---|---|---|---|---|
Put (GMv) | 995 ± 77.2 | 1016 ± 120.2 | 0.57 | 1134 ± 49.0 | 1162 ± 63.0 | 0.33 |
Put (GMd) | 0.59 ± 0.044 | 0.58 ± 0.046 | 0.85 | 0.57 ± 0.172 | 0.58 ± 0.116 | 0.90 |
premotor/SMA (MGv) | 8039 ± 695.1 | 8305 ± 1106.6 | 0.43 | 7220 ± 463.7 | 8630 ± 516.5 | 0.001(t = 3.85) |
Cau (GMv) | 1676 ± 112.3 | 1690 ± 225.1 | 0.85 | 1557 ± 111.5 | 1694 ± 162.2 | 0.07 |
Cau (GMd) | 0.62 ± 0.025 | 0.61 ± 0.029 | 0.1 | 0.6 ± 0.161 | 0.62 ± 0.123 | 0.60 |
vmPFC (MGv) | 2,13,599 ± 16028.3 | 2,17,222 ± 30353.5 | 0.69 | 2,04,172 ± 68.0 | 2,19,973 ± 15824 | 0.02(t = 2.50) |
Abbreviations AN: Anorexia, HC: healthy control, GMv: gray matter volume, GMd: gray matter density, Habit circuit regions including Put: putamen. Cau, caudate, premotor/SMA: premotor/supplementary motor area, goal-directed circuit regions including vmPFC: ventromedial prefrontal cortex.