Table 2.
Molecular characteristics of SLC5A5 genetic variants among pregnant women (n = 264) and the subset of lactating women (n = 55).
| All women (n = 246) | Sample of lactating women (n = 55) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Location | Gene structurea | Allelea | HWE | MAF | Genotype (n) | HWE | MAF | Genotype (n) | |||||
| Chr:bpa | (M):(m) | P-value | MM | Mm | mm | P-value | MM | Mm | mm | ||||
| rs121909177 | 19:17888397 | Exon | C:T | 1.0 | 0.007 | 225 | 3 | - | 1.0 | 0 | 52 | - | - |
| rs4808708 | 19:17890877 | Intron | G:A | 1.0 | 0.137 | 176 | 56 | 4 | 1.0 | 0.087 | 41 | 11 | 1 |
| rs7255301 | 19:17874025 | Intron | G:A | 0.0023 | 0.194 | 126 | 76 | 1 | 0.2802 | 0.188 | 30 | 14 | - |
| rs73520743 | 19:17883764 | Exon | A:C | 1.0 | 0.02 | - | 9 | 223 | 1.0 | 0.03 | - | 44 | 6 |
| rs112076606 | 19:17883785 | Intron | A:G | 0.448 | 0.214 | 2 | 55 | 81 | 1.0 | 0.214 | 1 | 16 | 17 |
| rs73520745 | 19:17884027 | Exon | G:A | 1.0 | 0.046 | 217 | 22 | - | 1.0 | 0.038 | 46 | 5 | - |
| rs775249401 | 19:17874645 | Intron | G:A | 1.0 | 0.056 | 217 | 25 | 1 | 1.0 | 0.028 | 43 | 9 | 1 |
| rs34850953 | 19:17872694 | Intron | G:T | 0.7938 | 0.077 | 202 | 33 | 2 | 1.0 | 0.038 | 45 | 7 | - |
| rs8103545 | 19:17875954 | Exon | C:T | 1.0 | 0.05 | 217 | 24 | - | 1.0 | 0.087 | 46 | 7 | - |
| Novel | 19:17983034 | 5′ prime UTR | C:C | 1.0 | 0.0 | 218 | - | - | 1.0 | 0 | 47 | - | - |
Chr, chromosome; bp, base pair; M, reference allele; m, alternative; HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency.
a
Ensembl release 96—April 2019, retrieved 03 April 2019 (24).