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. 2021 Jul 23;9:673959. doi: 10.3389/fpubh.2021.673959

Table 4.

Factors associated with knowledge of PEP.

OR (95% C.I.) p-value AOR (95% C.I.) (c) p-value
Country or region of birth
Portugal Reference category
Low prevalence regions (a) 0.81 (0.68–0.96) 0.014 0.59 (0.49–0.71) <0.001
South America 0.89 (0.80–0.99) 0.032 0.81 (0.71–0.91) <0.001
Africa 0.15 (0.13–0.18) <0.001 0.23 (0.19–0.27) <0.001
Eastern Europe and Asia 0.31 (0.23–0.43) <0.001 0.28 (0.20–0.38) <0.001
Gender
Male Reference category
Female 0.67 (0.60–0.74) <0.001 0.77 (0.69–0.86) <0.001
MTF 5.36 (3.81–7.54) <0.001 5.00 (3.48–7.18) <0.001
FTM 1.99 (0.51–7.70) 0.320 1.60 (0.40–6.41) 0.500
Age
≤ 25 years Reference category
26–49 years 1.14 (1.02–1.27) 0.02 1.23 (1.10–1.39) <0.001
≥ 50 years 0.30 (0.24–0.36) <0.001 0.60 (0.48–0.75) <0.001
Education
Basic (≤ 9 years) Reference category
Secondary (12 years) 2.86 (2.48–3.29) <0.001 2.14 (1.84–2.49) <0.001
University (Bachelors or higher) 5.08 (4.43–5.84) <0.001 3.69 (3.18–4.29) <0.001
Test year
2016 Reference category
2017 2.92 (2.45–3.49) <0.001 2.05 (1.70–2.48) <0.001
2018 3.18 (2.69–3.77) <0.001 1.88 (1.56–2.25) <0.001
2019 2.47 (2.10–2.91) <0.001 1.59 (1.33–1.89) <0.001
Key populations and other risk factors
MSM (b) 5.38 (4.85–5.97) <0.001 5.24 (4.47–6.14) <0.001
PWID (b) 0.89 (0.67–1.16) 0.893 0.94 (0.70–1.26) 0.680
SW (b) 2.26 (02.02–2.53) <0.001 2.46 (2.13–2.84) <0.001
Previous HIV test (b) 4.31 (3.78–4.91) <0.001 3.67 (3.19–4.22) <0.001
STi in last 12 months (b) 2.24 (1.86–2.71) <0.001 1.73 (1.41–2.12) <0.001
Condomless IC last 12 months (b) 0.66 (0.59–0.74) <0.001 0.73 (0.64–0.82) <0.001
Reactive HIV test result in same visit (b) 1.56 (1.12–2.19) 0.100 1.24 (0.84–1.84) 0.275
KnowsPrEP (b) 33.05 (28.70–38.07) <0.001 24.39 (20.85–28.53) <0.001

OR, crude odds ratio; C.I., confidence interval; AOR, adjusted odds ratio; MTF, male-to-female transgender; FTM, female-to-male transgender; MSM, men who have sex with men; SW, sex workers; PWID, people who inject drugs.

(a)Low prevalence regions include Western Europe (except Portugal), the United States of America, Canada, Oceania, and the Middle East.

(b)Reported OR is relative to responding “no” to the respective category, or not belonging to the corresponding key population.

(c)Adjusted for country or region of birth, gender, age, and education. In the corresponding categories, adjusted for the three remaining variables (e.g., gender is adjusted for country or region of birth, age, and education).