Table 3.
Adjusted odds ratio for three models used to analyze previous episodes of malaria and bet net usage among different genotypes. All models were adjusted for differences in age and sex among genotypes. All models were adjusted for multiple comparisons using Dunnett test. The proportional odds assumption was satisfied. SCT includes genotypes HbAS and HbAC. SCA includes genotypes HbSC and HbSS. Model 1 is the adjusted odds ratio for previous positive malaria diagnosis with HbAA as the reference group. Model 2 is the adjusted odds ratio for previous malaria diagnosis with SCT as the reference group. Model 3 is the adjusted odds ratio for bed net usage but excludes genotype HbCC.
| Adjusted Odds Ratio | OR | 95% CI | Adjusted P value |
|---|---|---|---|
| Model 1: Previous malaria episodes (ref=HbAA) | |||
| SCA vs HbAA | 4·6 | 2·66–8 | <0·0001 |
| SCT vs HbAA | 1·6 | 0·7–3·6 | 0·26 |
| F vs M | 0·87 | 0·53–1·4 | 0·58 |
| Age | 1 | 0·99–1·03 | 0·26 |
| Model 2: Previous malaria episodes (ref=SCT) | |||
| HbAA vs SCT | 0·65 | 0·3–1·4 | 0·26 |
| SCA vs SCT | 2·9 | 1·3–6·4 | 0·02 |
| F vs M | 0·87 | 0·5–1·4 | 0·59 |
| Age | 1 | 0·9–1·03 | 0·2 |
| Model 3: Mosquito net usage (excludes HbCC) (ref=yes & HbAA) | |||
| SCT vs HbAA | 7·2 | 2·5–20·6 | 0·0004 |
| SCA vs HbAA | 3·7 | 1·6–8·8 | 0·006 |
| F vs M | 1·3 | 0·7–2·4 | 0·43 |
| Age | 0·98 | 0·9–1 | 0·14 |