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. 2021 May 29;12(3):891–920. doi: 10.1016/j.jcmgh.2021.05.010

Table 1.

Summary of Multiplex Analysis of Hepatic Cytokine Expression (Liver Lysate)

Up-regulated only at early stages of NASH-bound mice Expressed in both NAFLD and NASH Up-regulated only in NASH mice Moderately reduced during reversal Reduced to baseline during reversal Suppressed in NASH and recovered during regression
IL28b (IFNλ3) IL17A KC (CXCL1) MIG (Cxcl9) KC (Cxcl1) CCL11 (eotaxin)
LIX (CXCL5) IL23 MIG (CXCL9) MIP-1α (CCL3) MCP1 (CCL2) TNF-β
IL31 TNFα IP-10 (CXCL10) IL1β IP-10 (CXCL10) IL12p40
IL22 VEGF MCP1 (CCL2) IL17A IL9 IL5
IL6 MIP2 (CXCL2) MIP-1α (CCL3) IL1α IL33
IL1α IL9 IFNγ LIF
IL33 IL21
LIF
IL1β
IFNγ
Rantes

IP-10, Interferon inducible protein 10; LIF, Leukemia inhibitory factor; MIP, Macrophage inflammatory protein; Rantes, Regulated on activation, normal T cell expressed and secreted; VEGF, vascular endothelial growth factor.