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. 2021 Jul 23;12:697157. doi: 10.3389/fimmu.2021.697157

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Copyright © 2021 Li, Li, Wu, Li, Yang, Wu, Xu, Luo, Gao, Fei and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of biomarkers in common DEGs. (A) Venn diagram showing common DEGs (logFC > 1, p < 0.05) to the GSE127952, GSE154926, and GSE40611 datasets and our RNA-Seq data. (B) Volcano map of the 28 common DEGs in our RNA-seq data. In the volcano plots, green and red points represent downregulated and upregulated genes, respectively, with logFC > 1, p < 0.05. (C–F) ROC curves based on pSS dataset GSE159574 predict candidate biomarkers related to T lymphocytes (C), B lymphocytes (D), immune response (E), and cell growth (F).