TABLE 3.

Univariable and multivariable analysis of the six-MRG signature and clinical factors in the TCGA osteosarcoma cohort.

Variables	Univariable analysis				Multivariable analysis
	HR	95% CI of HR		P	HR	95% CI of HR		P
		Lower	Upper			Lower	Upper
Gender (Female vs. Male)	0.546166519	0.24754378	1.205030749	0.134124815	0.539832412	0.218377899	1.334471275	0.181842468
Age (≤ 15 vs. > 15)	0.985348892	0.900215058	1.078533879	0.748865907	1.022160398	0.92253064	1.132549785	0.675290481
Site (lower limb vs. upper limb)	1.245115163	0.292335236	5.303198453	0.766834464	1.244072038	0.288740181	5.360235046	0.769482752
Risk score	1.000000003	1.000000001	1.000000005	0.001959531	1.000000003	1.000000001	1.000000005	0.003580904