Table 3.
Asthma |
Non-asthma |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
n | Baseline | Mid-intervention | Post-intervention | Follow-up | n | Baseline | Mid-intervention | Post-intervention | Follow-up | |
Intervention | ||||||||||
FEV1 (% predicted) | 29 | 93.5 ± 15.5 | 94.7 ± 14.1 | 92.2 ± 14.8 | 88.1 ± 15.8 | 90 | 93.9 ± 16.5* | 95.7 ± 13.8 | 97.1 ± 13.4 | 91.3 ± 15.4 |
FVC (% predicted) | 29 | 102.4 ± 13.2 | 102.5 ± 13 | 100.4 ± 14.7 | 94.9 ± 17.7 | 90 | 99.5 ± 13.8 | 100.8 ± 13.1 | 101.5 ± 18.3 | 94.5 ± 16.4 |
FEV1/FVC | 29 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 90 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 |
FEF25–75 (% predicted) | 29 | 78.2 ± 28.0 | 81.7 ± 22.5 | 77.7 ± 31.3 | 77.1 ± 24.1 | 90 | 83.1 ± 23.8* | 86.9 ± 23.4 | 89.2 ± 26.7 | 85.2 ± 25.4 |
PEF (% predicted) | 29 | 90.0 ± 18.5 | 89.5 ± 20.9 | 91.4 ± 19.1 | 85.7 ± 22.8 | 90 | 87.8 ± 19.8 | 90.0 ± 19.4 | 93.9 ± 17.9 | 88.5 ± 20.7 |
FeNO (ppb) | 29 | 40.3 ± 31.2 | 38.5 ± 31.3 | 38.6 ± 27.4 | – | 0 | – | – | – | – |
Control | ||||||||||
FEV1 (% predicted) | 68 | 90.1 ± 14.7 | 87.9 ± 19.4 | 92.8 ± 18.4 | 91.7 ± 13.5 | 155 | 96.1 ± 17.2* | 90.8 ± 19.5 | 96.1 ± 14.3 | 97.1 ± 16.6 |
FVC (% predicted) | 68 | 97.3 ± 14.6 | 96.0 ± 20.5 | 98.5 ± 20.1 | 97.0 ± 14.0 | 155 | 99.7 ± 15.0 | 92.9 ± 19.0 | 97.8 ± 13.7 | 98.1 ± 13.4 |
FEV1/FVC | 68 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 155 | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1 |
FEF25–75 (% predicted) | 68 | 75.6 ± 24.8 | 74.6 ± 29.0 | 79.0 ± 23.9 | 80.4 ± 21.3 | 155 | 88.2 ± 26.2* | 85.6 ± 26.2 | 91.9 ± 23.3 | 92.5 ± 24.5 |
PEF (% predicted) | 68 | 93.0 ± 21.1 | 89.7 ± 25.1 | 91.0 ± 15.2 | 91.5 ± 17.9 | 155 | 91.1 ± 21.4 | 87.6 ± 24.1 | 92.8 ± 17.0 | 92.8 ± 18.9 |
FeNO (ppb) | 70 | 43.6 ± 38.8 | 41.9 ± 39.7 | 41.4 ± 38.1 | – | 0 | – | – | – | – |
Note: Data are presented as n or mean ± SD as indicated.
Abbreviations: % predicted = expressed as a percentage of the age–sex–stature predicted value; FeNO = fractional exhaled nitric oxide; FEF25–75 = forced expiratory flow between 25% and 75% of vital capacity; FEV1 = forced expiratory volume in 1 s; FVC = forced vital capacity; PEF = peak expiratory flow; ppb = parts per billion.
p < 0.05, significantly different from Asthma at baseline.